H J Rupprecht

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BACKGROUND Despite the use of aspirin, there is still a risk of ischaemic events after percutaneous coronary intervention (PCI). We aimed to find out whether, in addition to aspirin, pretreatment with clopidogrel followed by long-term therapy after PCI is superior to a strategy of no pretreatment and short-term therapy for only 4 weeks after PCI. METHODS(More)
BACKGROUND Combination therapy with the ADP receptor antagonist ticlopidine plus aspirin has emerged as standard care after coronary stenting. Clopidogrel, a new ADP receptor antagonist, has greater molar potency than ticlopidine and better safety/tolerability. METHODS AND RESULTS Patients (n=1020) were randomized after successful stent placement and(More)
BACKGROUND Although the association of ticlopidine and aspirin has been shown to be superior to anti-vitamin K agents and aspirin after coronary stent implantation in low-risk patients, the latter combination has remained an unproven reference regimen for high-risk patients until recently. METHODS AND RESULTS We randomized 350 high-risk patients within 6(More)
OBJECTIVES To analyze the frequency of intra-abdominal Candida infection during acute necrotizing pancreatitis and to compare the outcome to patients without Candida infections. DESIGN Retrospective analysis of data from 37 patients with and without Candida infection. SETTING Surgical intensive care unit (ICU) in a university hospital. PATIENTS(More)
UNLABELLED Compared to other surgical disciplines the significance of V.A.C.-therapy is rarely noticed in abdominal surgery. This may be due to uncertainty in defining clear indications or lack of technical know-how. METHODS We report on five selected septic cases in abdominal surgery without clearly defined indications for V.A.C.-therapy (ischiorectal(More)
The visceral mass ofBiomphalaria glabrata uninfected or infected withSchistosoma mansoni was serially sectioned. The amount of hepatopancreas tissue and of parasite tissue was quantified. In pool-infected snails the volume of the whole visceral mass increased very significantly until week 6 and then decreased. Due to the growing parasites the volume of the(More)
BACKGROUND Various functional polymorphisms of the cholesteryl ester transfer protein ( CETP) gene influence CETP activity and the concentration of high-density lipoprotein (HDL) cholesterol. Beside other functional variants mainly the promoter polymorphism CETP/C-629A is currently discussed as a risk factor of coronary artery disease (CAD). We evaluated in(More)
Total protein, hemoglobin, glucose, and urea concentrations in hemolymph ofBiomphalaria glabrata were studied during a 12-week infection of the snails withSchistosoma mansoni. The results suggest an equilibrium between host and parasite metabolism, which is reached after about 6 weeks of infection. During the period studied, the protein spectrum of infected(More)