H Ishiguchi

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BACKGROUND Finnish-type familial amyloidosis (FAP-IV) is an autosomal, dominantly inherited disorder characterized by progressive polyneuropathy and lattice corneal dystrophy type II. The vast majority of families with this disorder originated from Finland. Only two families, in neighboring districts, have been reported in Japan previously. METHODS The(More)
The patient was a 70-year-old male with familial amyloidosis of Finnish type who complained of heat intolerance due to anhidrosis during outdoor activities in summer. A water-cooled TM-2 vest was tried for this patient to reduce his body heat during exercises. Following the morning activities including jogging in August his body temperature rose up to 38.0(More)
Familial amyloidosis, Finnish type (FAF), is a gelsolin-related systemic amyloidosis that has an autosomal-dominant inheritance pattern and is clinically characterized by progressive cranial neuropathy, corneal lattice dystrophy and skin changes such as cutis laxa, blepharochalasis, and lichen amyloidosis. A 70-year-old Japanese male proband, who was(More)
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