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In the present study, side preferences in spontaneous visual exploration were assessed systematically in 27 patients with idiopathic Parkinson's disease (IPD) and 17 age-matched controls. Assessment of initial visual exploration asymmetry (IVE) was based on the exploration of texture arrays requiring attentive oculomotor scanning. As shown in a previous(More)
In the last decade, brain-derived neurotrophic factor (BDNF) has become increasingly accepted as a central mediator of the effects of stress on neuronal plasticity and its implication for psycho-pathology. Neurotrophic functions of BDNF are implicated with neuronal survival, learning, memory, appetite and sleep. 1,2 The neurotrophin hypothesis is based on(More)
Difficulties in shifting of cognitive sets and perseverative behaviour have been shown to be part of the neuropsychology of Parkinson's disease, possibly due to frontal dysfunction. We have tested perseverative motor behaviour by assessing ability to generate random movement sequences in 15 patients with Parkinson's disease using the Breidt Perseveration(More)
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