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Proline-rich sequence recognition domains (PRD): ligands, function and inhibition.
- C. Freund, H-G Schmalz, J. Sticht, R. Kühne
- Biology, Medicine
- Handbook of experimental pharmacology
Low-affinity protein-protein interactions (PPI) between domains of modular proteins and short, solvent-exposed peptide sequences within their binding partners play an essential role in intracellular… Expand
Gram-scale synthesis of pinusolide and evaluation of its antileukemic potential.
- E. Shults, J. Velder, +6 authors A. Prokop
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 15 August 2006
Pinusolide (1), a known platelet-activating factor (PAF) receptor binding antagonist, was synthesized from lambertianic acid (2), a labdane-type diterpene readily accessible in multigram quantities… Expand