H G Mandel

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The rate of DNA synthesis was determined in rats with developing and established two-kidney, one clip renal hypertension. Rate of DNA synthesis was measured as [3H]thymidine incorporation into DNA per hour. After stenosis of the renal artery, blood pressure increased over a 2-week period. Five days after clipping, there was an increase in the rate of aortic(More)
Because of the prospect of a serious decline in the nation's biomedical research capacity owing to diminished federal appropriations, temporary measures should be initiated promptly by the National Institutes of Health to preserve the stability of resources and diversity of research required for future productivity. It is recommended that the available(More)
Proliferation of rat neurological cells was quantified following a lesion of the frontal cortex, with the rate of incorporation of intraventricularly administered [3H]thymidine ([3H]TdR) into cortical DNA serving as an index of glial proliferation. Incorporation of [3H]uridine into the corresponding RNA fractions did not serve this purpose. The(More)
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