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Maternal care boosted by paternal imprinting in mammals
In mammals, mothers are the primary caregiver, programmed, in part, by hormones produced during pregnancy. High-quality maternal care is essential for the survival and lifelong health of offspring.Expand
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A Role for the Placenta in Programming Maternal Mood and Childhood Behavioural Disorders
Substantial data demonstrate that the early‐life environment, including in utero, plays a key role in later life disease. In particular, maternal stress during pregnancy has been linked to adverseExpand
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Loss of offspring Peg3 reduces neonatal ultrasonic vocalizations and increases maternal anxiety in wild-type mothers
Abstract Depression and anxiety are the most common mental health conditions during pregnancy and can impair the normal development of mother-infant interactions. These adversities are associatedExpand
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Programming of maternal behaviour by the placenta: A novel animal model
between prenatal maternal anxiety with the child COMT and BDNF genotypes, in cognitive and emotional outcomes respectively. The underlying mechanisms for such fetal programming are still not wellExpand
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Fetal growth restriction in a genetic model of sporadic Beckwith–Wiedemann syndrome
ABSTRACT Beckwith–Wiedemann syndrome (BWS) is a complex imprinting disorder involving fetal overgrowth and placentomegaly, and is associated with a variety of genetic and epigenetic mutationsExpand
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Epigenetic regulation of placental endocrine function
Exploring a novel mechanism instructing maternal care and influencing offspring outcomes
Pregnancy induces numerous changes in the physiology of the mother as she adapts to the metabolically demanding fetus developing within her womb. It is during this period of intense physiologicalExpand
A systems approach to understanding placental signalling