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Substantial data demonstrate that the early-life environment, including in utero, plays a key role in later life disease. In particular, maternal stress during pregnancy has been linked to adverse… (More)
In mammals, mothers are the primary caregiver, programmed, in part, by hormones produced during pregnancy. High-quality maternal care is essential for the survival and lifelong health of offspring.… (More)
Depression and anxiety are the most common mental health conditions during pregnancy and can impair the normal development of mother-infant interactions. These adversities are associated with low… (More)
Beckwith-Wiedemann syndrome (BWS) is a complex imprinting disorder involving fetal overgrowth and placentomegaly, and is associated with a variety of genetic and epigenetic mutations affecting the… (More)
Pregnancy induces numerous changes in the physiology of the mother as she adapts to the metabolically demanding fetus developing within her womb. It is during this period of intense physiological… (More)
between prenatal maternal anxiety with the child COMT and BDNF genotypes, in cognitive and emotional outcomes respectively. The underlying mechanisms for such fetal programming are still not well… (More)