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Estimates of osteoporosis (OP) prevalence based on bone mineral density testing and fracture occurrence may be imprecise for small demographic groups. Medicare data are a useful supplemental source of information on OP. We studied people ages ≥65 years covered by Medicare 2005. Cases of presumed OP were beneficiaries with physician services or inpatient(More)
The comparative effectiveness of alendronate and risedronate has received limited evaluation. Among 19,063 new users of bisphosphonates, risedronate users had a higher relative rate of hip fracture compared to alendronate users, but the difference in absolute fracture rate was small. We conclude that the agents have comparable efficacy. Bisphosphonates(More)
Based upon interest in a bisphosphonate drug holiday, we evaluate the risk for hip fracture after bisphosphonate discontinuation. Among women compliant with bisphosphonates for ≥2 years, the risk of hip fracture was increased after discontinuation, although with higher compliance and a longer duration of preceding bisphosphonate therapy, this risk was(More)
OBJECTIVES To evaluate the association between zolpidem use and the risk of Alzheimer's disease among older people. DESIGN A retrospective cohort study using data from 2001 to 2011 from the National Health Insurance Research Database. SETTING Taiwan. PARTICIPANTS A total of 6,922 patients aged 65 years or older enrolled from January 2002 to December(More)
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