H. Brian Halsall

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A study comparing the electrophoretic separation performance attainable from microchips molded by masters fabricated using conventional CNC machining techniques with commercial microchips, wire imprinted microchips, and microchips from LIGA molding devices is presented. An electrophoresis-based detection system using fluorescence microscopy was used to(More)
A competitive enzyme-linked immunoabsorbent assay based on the flow-injection amperometric detection of p-aminophenol has been investigated with use of the materials and general procedure of a commercial kit for the determination of theophylline in human serum. The antibody is immobilized on glass beads, and the enzyme label is alkaline phosphatase (EC(More)
Fluorescently labeled beads may be utilized in transparent microfluidic devices to facilitate a variety of immunoassay based chemical measurements. We investigate the ability to visualize, quantitate, and reduce undesirable adsorption of beads within a polydimethylsiloxane (PDMS) microchannel device. These methods are prerequisites to the design of(More)
An immunological method based on labeling an antigen with an electroactive group detectable by differential pulse polarography has been demonstrated. Estriol labeled with mercuric acetate is electroactive, giving a reduction wave at -300 millivolts versus a standard calomel electrode. Addition of estriol antibody to 4-mercuric acetate estriol diminishes the(More)
—This paper describes the development of a label-free immunosensor using carbon nanotube array electrodes. Highly aligned multi-walled carbon nanotubes were grown by chemical vapor deposition using a metallic catalyst, Fe/Al 2 O 3 /SiO 2 , on Si wafers. Harvested towers were cast in epoxy and polished on both ends; one end being for electrical connection(More)
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