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Aberrant expression of the RON receptor tyrosine kinase has been implicated in the pathogenesis of epithelial tumours. The aim of this study was to determine RON expression in various normal epithelial cells and their corresponding tumours by immunohistochemistry. The role of RON in regulating tumourigenic phenotypes was also studied using thyroid cancer(More)
OBJECTIVE To elucidate the potential of monoclonal antibodies (mAbs) of culture filtrate protein 10 (CFP-10) and early secretory antigenic target 6 (ESAT-6) in tuberculosis (TB) diagnosis. DESIGN We generated and characterised monoclonal and polyclonal antibodies against Mycobacterium tuberculosis-specific antigens ESAT-6 and CFP-10 by immunising BALB/c(More)
Reservoir effect of electromigration (EM) reliability has been investigated in Cu/low-k dual-damascene interconnects with varied reservoir lengths. However, the effectiveness of the reservoir effect in improving EM reliability as a function of line width has not been studied till now. In this work, experimental studies of the reservoir effect for both(More)
An excitation function of proton rapidity distributions for different centralities is reported from AGS Experiment E917 for Au+Au collisions at 6, 8, and 10.8 GeV/nucleon. The rapidity distributions from peripheral collisions have a valley at midrapidity which smoothly change to distributions that display a broad peak at midrapidity for central collisions.(More)
We present results for antilambda and antiproton production in Au+Au collisions at 11.7 A GeV/c including spectra and extracted invariant yields for both species in central and peripheral collisions in the rapidity range 1.0<y<1.4. The antilambda yield increases from dN(Lambda;)/dy = 1.2(+0.7+0.2)(-0.6-0.2)x10(-3) in peripheral collisions to(More)
A method consisting of solvent extraction followed by liquid chromatography-quadrupole-time of flight- tandem mass spectrometry analysis was developed for the identification of Imazaquin and its metabolite. The relationships between detector response and sample concentrations showed a high degree of linearity (r > 0.998) over the range 0.03-10 microg/g. The(More)
Olanzapine is a novel antipsychotic drug. Recently it has been applied to clinical research. For the determination of olanzapine in plasma a reversed-phase HPLC method has been established. An aqueous solution of 0.25% ascorbic acid was added into the plasma sample and kept at -20 degrees C. Olanzapine can be separated on a Zorbax ODS column with a mobile(More)
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