H B Liao

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The forkhead-associated (FHA) domain is a 55-75 amino acid residue module found in >20 proteins from yeast to human. It has been suggested to participate in signal transduction pathways, perhaps via protein-protein interactions involving recognition of phosphopeptides. Neither the structure nor the ligand of FHA is known. Yeast Rad53, a checkpoint protein(More)
Plasmon-resonant gold nanorods are demonstrated as low back-scattering albedo contrast agents for optical coherence tomography (OCT). We define the backscattering albedo, a , as the ratio of the backscattering to extinction coefficient. Contrast agents which modify a within the host tissue phantoms are detected with greater sensitivity by the differential(More)
The optical properties of plasmonic dipole and bowtie nanoan-tennas are investigated in detail using the Green's tensor technique. The influence of the geometrical parameters (antenna length, gap dimension and bow angle) on the antenna field enhancement and spectral response is discussed. Dipole and bowtie antennas confine the field in a volume well below(More)
The forkhead-associated (FHA) domain is a protein module found in many proteins involved in cell signaling in response to DNA damage. It has been suggested to bind to pThr sites of its target protein. Recently we have determined the first structure of an FHA domain, FHA2 from the yeast protein Rad53, and demonstrated that FHA2 binds to a pTyr-containing(More)
Herein we report the bulk synthesis of single crystalline GaN nanowires. Laser ablation of a composite target of GaN and a catalytic metal generates liquid nanoclusters that serve as reactive sites confining and directing the growth of crystalline nanowires. Field emission scanning electron microscopy (FE-SEM) shows that the product primarily consists of(More)
Using a sample of 58 million J/ψ events recorded in the BESII detector, the decay J/ψ → ωπ + π − is studied. There are conspicuous ωf 2 (1270) and b 1 (1235)π signals. At low ππ mass, a large broad peak due to the σ is observed, and its pole position is determined to be (541 ± 39)-i (252 ± 42) MeV from the mean of six analyses. The errors are dominated by(More)
The mechanism of phosphatidylinositol-specific phospholipase C (PI-PLC) has been suggested to resemble that of ribonuclease A. The goal of this work is to rigorously evaluate the mechanism of PI-PLC from Bacillus thuringiensis by examining the functional and structural roles of His-32 and His-82, along with the two nearby residues Asp-274 and Asp-33 (which(More)
Gallium nitride ͑GaN͒ thin films with a wurtzite structure were grown on fused silica ͑FS͒ substrates by pulsed laser ablation of a liquid gallium target in the presence of ammonia gas. X-ray diffraction measurement shows a single c-axis orientation for the GaN film grown with a thin ͑Ͻ1000 Å͒ zinc oxide ͑ZnO͒ film as an alignment layer. There is a great(More)
The enhanced optical nonlinearity enabled by localized plasmonic fields has been well studied for all-optical switching processing (AOSP) devices for future optical communication systems. In this work, plasmonic photonic crystals with a nonlinear polycarbonate/polymethine blend cladding layer are designed to enhance the third harmonic generation (THG) at(More)