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Journals and Conferences
Two dimeric naphthoquinones, diospyrin and isodiospyrin, isolated from the root of Diospyros piscatoria (Gurke), a common ingredient in several folk medicines, have been shown to have a broad spectrum of antibacterial activity. The minimum inhibitory concentrations (MICs) of diospyrin against Streptococcus pyogenes ATCC 12344 and Streptococcus pneumoniae… (More)
A total of 1,847 serum samples obtained from human subjects in various areas of Nigeria (North, East and West) were tested for the presence of rubella haemagglutination inhibition antibodies. The results showed that an average of 68% of the Nigerian population studied possessed rubella antibody.
Quercetin-7,4'-disulphate (1) quercetin (2) quercetin-3',4'-disulphate (3) quercetin-3,4'-diacetate (4) rutin (5) and quercetrin (6) were isolated from the ethyl acetate soluble fraction (ESM) of the crude methanolic leaf extract of Alchornea laxiflora. Purification of these compounds was carried out by column chromatography utilising sephadex LH 20 and… (More)
The prevalence rate of HBsAg carrier state in Nigerian pregnant women was determined to be 11.2 per cent. One third of infants born to these carrier mothers had persistent antigenaemia during an eight month follow-up period.
Using two serological techniques, eight Nigerian West Nile virus isolates were investigated to determine antigenic relationships among them, and to find out if these virus isolates were related to West Nile virus strains from the different zoogeographic areas of the world. One virus differed significantly from the seven other strains and was later found to… (More)
Seven strains of West nile virus isolated in Nigeria were investigated for their ability to form plaques in monkey kidney cell monolayers. Five strains antigenically related to one another produced plaques of about the same size 3 to 4 days after the addition of the overlay medium. The two other strains closely related to each other produced no plaques.… (More)
The newly developed single-radial-haemolysis technique was employed in this study for screening of sera for detection of antibodies to three Nigerian togaviruses. This technique was compared with the standard haemagglutination-inhibition method. A close correlation between the two techniques was observed.
Employing neutralization tests, eight Nigerian strains of West Nile virus were investigated to determine antigenic relationships among them. One virus strain differed so significantly from the others and was later found to be a strain of Usutu virus. The other seven strains were differentiated into two serological intratypic groups dependent on their cross… (More)
Electron micrographs of a silver resistant strain of Pseudomonas aeruginosa grown in the presence of 50 micrograms/ml Ag+ indicate that the surviving cells are resistant at the level of the cytoplasmic membrane. Spheroplasts of the resistant strain were not lysed by 1 h contact with 8 micrograms/ml Ag+, but were 36% and 22% lysed by 1 h contact with 20… (More)