H A Huiges

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Surface antigens on melanoma cells were studied with an MIF method applied for monolayers of cultured cells. Human sera were used with indirect immunofluorescence. Preparations were fixed in methanol after staining. Reactions of sera with antibodies against trasplantation antigens displayed a fine granular fluorescence. This appearance was abolished by(More)
Immune complexes in PMN cells of sixty-five patients with malignant melanoma were studied by scoring the cells for IgG and complement inclusions. Group (a), consisting of thirty-four patients free from tumour after surgical therapy, showed a median IgG score of 17, which was not statistically different from the control group (n = 11), with a median score of(More)
In vitro lymphocyte function was evaluated in 61 patients with different clinical stages of malignant melanoma. Thirty-one of these patients had localized disease, 13 regional metastases, 10 distant lymph node or skin metastases, and 7 visceral metastases. Following immunization, in vitro lymphocyte reactivity to three antigens (diphtheria toxoid, tetanus(More)
Jansen, H. M., The, T. H., de Gast, G. C., Huiges, H. A., Esselink, M. T., Van der Wal, A. M., and Orie, N. G. M. Thorax, 32, 706-710. Immunoglobulin and complement inclusions in peripheral blood polymorphonuclear leucocytes of patients with bronchial carcinoma. Inclusions in peripheral blood polymorphonuclear leucocytes (PMN) of 23 patients with bronchial(More)
The primary immune response to Helix pamatia haemocyanin (HPH) was investigated in sixty-one patients with various clinical signs of malignant melanoma and compared to that of controls. Anti-HPH antibody response was only found abnormal in patients with widespread disease and visceral metastases, apparent from decreased 7S and increased 19S antibody levels.(More)
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