Learn More
The present study examined the influence of subjective factors on temporary threshold shifts (TTS) after exposure to noise and music. Two groups of subjects, those who indicated liking and those who indicated disliking pop/rock music, were exposed to both noise and music on separate occasions. Subjects who liked the music exhibited less TTS following music(More)
Guinea pigs were exposed to 120 dB white noise for 30 min and evidenced a four-fold elevation in plasma concentration of the potent vasoconstricting hormone angiotensin II (AII). Anesthetized animals received intra-arterial injections of AII at doses that approximated the endogenous levels measured following noise exposure. A marked decrease in skin blood(More)
Wistar-Kyoto rats (WKY) were intra-arterially infused with angiotensin II (AII) or phenylephrine for 10 min. Both vasoactive compounds produced an initial increase in cochlear blood flow (CoBF) as measured by laser Doppler flowmetry, followed by a slow steady return to baseline, despite sustained elevations in systemic blood pressure. These results suggest(More)
This study investigated blood pressure in guinea pigs while they were 1) alert and free moving, 2) anesthetized with different anesthetics, and 3) exposed to continuous, 115 dB SPL white noise under anesthesia. The animals were prepared with a carotid artery catheter and permitted to recover for 48 h before blood pressure levels were measured. Mean arterial(More)
Previous investigations in our laboratory have measured significant increases in the circulating levels of the potent vasoconstrictive hormone, angiotensin II (AII; 26 and 64 pg/100 microliters plasma, normal and noise exposed, respectively), during and following noise exposure in the alert rat (Wright et al., 1981). In the present study, these levels were(More)
This paper compiles the results from seven experiments which have investigated noise exposure effects on histological measures of the cochlear vasculature and red blood cells. Two of these studies included at least two experimental conditions and all evaluated numerous histological parameters in several cochlear vessels. The combined results suggest that(More)
Anesthetized guinea pigs were given arterial bolus injections of saline or varying nicotine concentrations. Blood flow through the cochlea and skin were measured via laser Doppler and arterial blood pressure via an arterial cannula. Cochlear blood flow increased with low doses of nicotine but decreased with the highest dose, while blood pressure increased(More)
The relationship among a personality measure, peripheral vascular measures, and audiometric indexes of susceptibility to noise-induced hearing loss were studied. Seventy-four male human subjects were selected based upon their responses to a self-report measure of coronary-prone behaviors. Coronary-prone, nonprone, and median scores with normal hearing were(More)
Our laboratory has previously measured significant elevations in plasma angiotensin II concentrations accompanying brief intense noise exposures in rodents. The present investigation was designed to evaluate the effects of noise induced elevations in water consumption and blood pressure in normotensive female rats. The durations of noise exposure simulated(More)
Previous studies in our laboratory (Quirk et al., 1988) noted significantly impaired elevations in cochlear blood flow (CoBF) during systemic infusion of the potent vasoconstrictive agent angiotensin II (AII) in the spontaneously hypertensive rat (SHR) as compared with the normotensive Wistar-Kyoto (WKY) rat, despite similar increases in systemic blood(More)