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AIMS To address the incremental usefulness of biomarkers from different disease pathways for predicting risk of death in heart failure (HF). METHODS AND RESULTS We used data from consecutive patients treated at a structured multidisciplinary HF unit to investigate whether a combination of biomarkers reflecting ventricular fibrosis, remodelling, and(More)
INTRODUCTION AND OBJECTIVES To update the prevalence of metabolic syndrome and associated coronary risk in Spain, using the harmonized definition and the new World Health Organization proposal (metabolic premorbid syndrome), which excludes diabetes mellitus and cardiovascular disease. METHODS Individual data pooled analysis study of 24,670 individuals(More)
The (87)Rb-(87)Sr internal isochrons for five rocks yield an age of 3.65 +/-0.05 x 10(9) years which presumably dates the formation of the Sea of Tranquillity. Potassium-argon ages are consistent with this result. The soil has a model age of 4.5 x10(9) years, which is best regarded as the time of initial differentiation of the lunar crust. A peculiar rock(More)
INTRODUCTION AND OBJECTIVES To estimate the prevalence of cardiovascular risk factors in individuals aged 35-74 years in 10 of Spain's autonomous communities and determine the geographic variation of cardiovascular risk factors distribution. METHODS Pooled analysis with individual data from 11 studies conducted in the first decade of the 21st century. The(More)
OBJECTIVE To estimate the prevalence, detection, treatment and degree of control of cardiovascular risk factors in Extremadura. DESIGN Cross-sectional study. SETTING Population study in Don Benito-Villanueva de la Serena health area (Badajoz). PARTICIPANTS A random sample of the people between 25 and 79 years, who lived in this area, was selected. (More)
INTRODUCTION AND OBJECTIVES The treatment and control of cardiovascular risk factors both play key roles in primary prevention. The aim of the present study is to analyze the proportion of primary prevention patients aged 35-74 years being treated and controlled in relation to their level of coronary risk. METHODS Pooled analysis with individual data from(More)
OBJECTIVE The aim of the present study was to assess the concurrent and construct validity of two diet-quality indices, a modified Mediterranean diet score (mMDS) and a Mediterranean-like diet score (MLDS) additionally incorporating unhealthy food choices, as determined by an FFQ. DESIGN A validation study assessing FFQ intake estimates compared with ten(More)
OBJECTIVES The purpose of this study was to assess the value of estimated glomerular filtration rate (eGFR) calculated by different formulas for predicting the risk of death in heart failure (HF) outpatients. BACKGROUND Patients with both HF and renal insufficiency have a poor prognosis. Three formulas are mostly used to assess renal function:(More)
BACKGROUND Multimorbidity is associated with higher mortality, increased disability, a decline in functional status and a lower quality of life. The objective of the study is to explore patterns of multimorbidity in an elderly population. METHODS 328 community inhabitants aged 85 years were included. Socio-demographic variables and data from the global(More)