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  • Oleg V. Evgenov, Pál Pacher, Peter Dr. Schmidt, György Haskó, Harald Hhw Schmidt, J. -P. Stasch
  • Medicine, Chemistry
  • Nature Reviews Drug Discovery
  • 2006 (First Publication: 1 September 2006)
  • Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme activated by nitric oxide (NO). Impaired bioavailability and/or responsiveness to endogenous NO has been implicated in theContinue Reading
  • György Haskó, Csaba Szabó, Zoltán H. Németh, Vladimir Kvetan, Stephen M Pastores, E. Sylvester Vizi
  • Biology, Medicine
  • Journal of immunology
  • 1996 (First Publication: 15 November 1996)
  • Adenosine released into the extracellular space by immunologic and nonimmunologic stimuli has been shown to regulate various immune functions. In this study we report that i.p. pretreatment of miceContinue Reading
  • György Haskó, David G. Kuhel, +5 authors Csaba Szabó
  • Biology, Medicine
  • FASEB journal : official publication of the…
  • 2000 (First Publication: 1 October 2000)
  • Interleukin 12 (IL-12) is a crucial cytokine in the regulation of T helper 1 vs. T helper 2 immune responses. In the present study, we investigated the effect of the endogenous purine nucleosideContinue Reading
  • Partha Mukhopadhyay, Mohanraj Rajesh, György Haskó, Brian J. Hawkins, Muniswamy Madesh, Pál Pacher
  • Medicine, Biology
  • Nature Protocols
  • 2007 (First Publication: 1 September 2007)
  • Annexin V and Sytox Green are widely used markers to evaluate apoptosis in various cell types using flow cytometry and fluorescent microscopy. Recently, a novel fluoroprobe MitoSOX Red was introducedContinue Reading
  • Partha Mukhopadhyay, Mohanraj Rajesh, +5 authors Pál Pacher
  • Biology, Medicine
  • American journal of physiology. Heart and…
  • 2007 (First Publication: 16 October 2007)
  • Doxorubicin (DOX) is a potent available antitumor agent; however, its clinical use is limited because of its cardiotoxicity. Cell death is a key component in DOX-induced cardiotoxicity, but itsContinue Reading