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BACKGROUND: The present study was designed to determine the efficacy and safety of Niaspan (Kos Pharmaceuticals, Inc, Hollywood, FL), a new controlled-release formulation of niacin, in the treatment of primary hyperlipidemia, the occurrence and severity of flushing events, and potential adverse effects, particularly hepatotoxicity. METHODS AND RESULTS: The(More)
treatment of asthma where there is a history of the excessive use of aerosol broncho-Pressurized Aerosols in Asthma SIR,-Recently correspondents have suggested that excessive amounts of sympa-theticomimetic drugs cause cardiac arrhythmias in asthmatics (4 March, p. 563, 25 March, p. 756). In this context I think the following case is of interest. The(More)
Environmental Protection Agency (EPA) and the California EPA] conduct health assessments of environmental chemicals to determine the likelihood of human health hazard and to establish levels of exposure considered as health protective. To derive quantitative toxicity values (i.e., cancer slope factors or reference doses/concentrations) for comparison to(More)
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