Guyang Huang

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The small nucleolar RNAs (snoRNA) have been implicated in ribosome biogenesis, based on: i) subeellular localization with the rDNA transcriptional apparatus, ii) demonstrated associations with various preand mature rRNA species, iii) complementarity with rRNA and iv) disruption of precursor rRNA processing which accompanies loss of two specific snoRNA(More)
The transcription factor RUNX1 is a master regulator of hematopoiesis. Disruption of RUNX1 activity has been implicated in the development of hematopoietic neoplasms. Recent studies also highlight the importance of RUNX1 in solid tumors both as a tumor promoter and a suppressor. Given its central role in cancer development, RUNX1 is an excellent candidate(More)
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