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BACKGROUND Moderate anticoagulation may be proposed to reduce the risk of hemorrhage for certain patients with a mechanical prosthesis, but the consequences for risk of thromboembolism are debated. METHODS AND RESULTS The purpose of the AREVA trial was to compare moderate oral anticoagulation (international normalized ratio [INR] of 2.0 to 3.0) with the(More)
BACKGROUND There remains controversy concerning the association between myocardial dysfunction diagnosed soon after acute myocardial infarction (AMI), and subsequent quality of life. AIMS We searched for a correlation between criteria of myocardial dysfunction assessed within the first month after AMI, and quality of life perceived 1 year later. METHODS(More)
The aim of this retrospective study was to review the outcome of 216 patients (pts), investigated for severe mitral regurgitation (MR) between January 1980 and December 1987. Definition of 'severe' was mainly clinical: MR sufficiently advanced for the cardiologist to investigate whether surgery should be imminent. One hundred and sixty two pts (group 1)(More)
AIMS The purposes of this study were to determine the clinical features and to identify prognostic factors of abscesses associated with infective endocarditis. METHODS AND RESULTS During a 5-year period from January 1989, 233 patients with perivalvular abscesses associated with infective endocarditis were enrolled in a retrospective multicentre study. Of(More)
In order to assess the prevalence and prognosis of ventricular arrhythmias in patients with surgical mitral regurgitation, a prospective cooperative study was undertaken in 14 French cardiological centres. Seventy-nine patients (45 men, 34 women, average age 62.8 +/- 12.8 years), who underwent mitral valvuloplasty (44 cases) or valve replacement (35 cases),(More)
OBJECTIVE This study sought to compare characteristics and management of myocardial infarction in men and women, and whether a difference in management would translate into a difference in in-hospital mortality. METHODS AND RESULTS Data were prospectively collected in 2,519 patients (801 women) admitted in all hospitals in three departments in the(More)
OBJECTIVES The purpose of this study was to assess the quality of the management of infective endocarditis. BACKGROUND Although many guidelines on the management of infective endocarditis exist, the quality of this management has not been evaluated. METHODS We collected data on all patients (116) hospitalized with infective endocarditis over 1 year in(More)
M ore and more patients are operated on during the active phase of infective endocarditis (IE). 1 Between 1991 and 1999, in France, the rate of cardiac surgery has increased from 31% to 50%. 1 This may, at least in part, explain the concomitant decrease of in hospital mortality, from 22% to 17%. 1 Nonetheless, the indications for cardiac surgery and its(More)
Three problems hamper the prognosis of patients who survive the initial phase of infective endocarditis (IE): the rate of IE recurrence is 0.3-2.5/100 patient years, about 60% of patients will have to be operated on at some time, 20-30% during the initial stay, 30-40% during the following 5-8 years; five-year survival after the hospital phase is about 75%(More)