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The cholinergic projection from the nucleus basalis magnocellularis to the neocortex has been implicated in normal memory function and in the dementia of Alzheimer's disease. In order to investigate… (More)
Three groups of rats received either unilateral fimbria-fornix lesions by aspiration through the overlying cingulate cortex (group I), a fimbria-fornix lesion followed by an intrahippocampal… (More)
Motor behavior was investigated in rats following acute and chronic gamma-aminobutyric acid (GABA) microinfusions into the nucleus basalis. For acute treatment, the rats received GABA (100 micrograms… (More)
Pharmacological studies have, over the past two decades, established the involvement of acetylcholine in learning and memory processes (Deutsch, 1971; Bartus et al., 1982). This link has been… (More)
Nerve growth factor (NGF) is a well-characterized protein that acts as a neurotrophic factor for catecholaminergic neurons of the peripheral sympathetic nervous system and for a subpopulation of… (More)
The effects of different postoperative physical environments on novelty seeking and maze learning were tested in rats that sustained dorsal hippocampal lesions at 30 days. After surgery, rats were… (More)