Guy-Henri Muller

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Purpose: The aim of this study was to determine the energy (J/mm3 tumor volume) and temperature required for a complete laser-induced thermotherapy (LITT) of experimental liver tumors, and to find out causes and areas of local recurrence followed by incomplete treatment. Methods: In VX-2 tumor-bearing rabbits LITT was performed using(More)
Human cytomegalovirus (HCMV) is the most common cause of viral intrauterine infection and fetal damage largely due to maternal primary infection. Virological procedures which are able to detect HCMV fetal infection were evaluated. HCMV IgG antibodies were detected in 62.5% of the pregnant women and 1.47% had a primary infection. From March, 1992 to August,(More)
Treatment of subdiaphragmatic Hodgkin's diseases with combined radio- and chemotherapy results in castration of more than 80% of the women treated, despite oophoropexy. We suggest a new technique of subcutaneous ovarian grafting which provides full protection against irradiation and preserves both ovarian function and fertility. To be successful this(More)
Renal tubular obstruction is an important contributor to the pathophysiology of acute renal failure. Based on the previous findings of the role played by arginine-glycine-aspartic acid (RGD) recognizing integrins in tubular obstruction, this study examined the effect of RGD peptides on the course of ischemic acute renal failure in rats. For in vivo studies,(More)
A variant strain of Candida albicans incapable of hyphal production at 37 degrees C was used to study the role of germ tube formation in the pathogenesis of experimental vaginal candidiasis in rats. No difference was observed in the in vitro adherence at 25 degrees C of blastoconidia of the variant strain to vaginal epithelial cells when compared with the(More)
The in vivo-in vitro hepatocyte assay, a short-term test that is useful for detecting potential rodent hepatocarcinogens, has been extended to the CD-1 mouse. Male CD-1 mice, 50-100 days old, were dosed orally with N-nitrosodimethylamine (NDMA), trichloroethylene (TCE), 2-acetylaminofluorene (2-AAF), 4-acetylaminofluorene (4-AAF), phenobarbital (PB) or a(More)
To assess the molybdenum supply and requirements of preterm infants, Mo concentration was determined in milk from mothers of 6 term and 11 preterm newborns; no difference was found between fore- and hindmilk and no diurnal variations were found during 24-h collections. Respective values (means +/- SD) of term and preterm milks were 10.2 +/- 3.7 and 4.0 +/-(More)
Comparison of itraconazole (R51,211) and ketoconazole in the treatment of experimental candidal vaginitis in rats on schedules of 3 and 5 days revealed significantly superior results with itraconazole at all dosages (1.0 to 7.5 mg/kg) studied, but was particularly evident at 1.0 and 2.5 mg/kg. A single 25-mg/kg dose of itraconazole was as effective as 5(More)
Adherence of 14C-glucose labeled Candida albicans to vaginal epithelial cells was measured in the presence of 10 potential inhibitory sugars at concentrations of 5 to 150 mg per ml for 90 minutes at 37 degrees C. In competitive inhibition experiments, no inhibition of adherence was seen with any sugar at any concentration. On the contrary, with the(More)