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BACKGROUND The combination of salmeterol and fluticasone propionate (SFC) and tiotropium bromide (TIO) are commonly used treatments in chronic obstructive pulmonary disease (COPD) but there are few data on their effectiveness when used together. We compared the effects of SFC 50/500 microg twice daily in addition to TIO 18 microg once daily with the(More)
OBJECTIVE The aim was to develop a digital video contrast angiographic method for assessing global left ventricular function and volume in vivo in the rat and then to apply it to a study of ventricular remodelling after coronary occlusion, with and without reperfusion. METHODS Digital contrast angiography was performed on 29 rats, including the following(More)
A 39-year-old nulliparous woman became breathless after a caesarean section. CT pulmonary angiography (fig 1) showed no filling defect but cysts, small bilateral effusions and thickened interlobular septa were visible consistent with a possible diagnosis of lymphangioleiomyomatosis (LAM). An open lung biopsy performed 11 months later showed that the lung(More)
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