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High-risk human papillomavirus (hr-HPV) infection is necessary but not sufficient for cervical cancer development. Recently, P16INK4A gene silencing through hypermethylation has been proposed as an(More)
OBJECTIVE To characterize decorin and chondroitin sulfate (CS) expression in lichen sclerosus (LS). STUDY DESIGN Thirty-one untreated vulvar LS lesions were biopsed, and hematoxylin-eosin-stained(More)
Methylation is a chemical modification in which a methyl group (CH3) is added to the cytosine in the promoter region of the gene. It involves a very frequent epigenetic event that is found in many(More)
This study investigated the rate of human papillomavirus (HPV) persistence, associated risk factors, and predictors of cytological alteration outcomes in a cohort of human immunodeficiency(More)