Gustavo Pereira Cosenza

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ETHNOPHARMACOLOGICAL RELEVANCE Bitter tasting plant species are used as tonics and have been previously used to treat intermittent fevers in Brazil, the principal symptom of malaria. Many of these species were named quina and were used as substitutes of Cinchona spp., the source of quinine. AIM OF THE STUDY To present data on these bitter species named(More)
ETHNOPHARMACOLOGICAL RELEVANCE Ampelozizyphus amazonicus Ducke is a plant used in Brazilian folk medicine to both prevent malaria and act as a depurative. AIM OF THE STUDY We have investigated the effects of an ethanol crude extract of roots of Ampelozizyphus amazonicus (CEAaD), a chemically characterized saponin mixture (SAPAaD), as well as a(More)
Plants continue to be an important source of new bioactive substances. Brazil is one of the world's mega-diverse countries, with 20 % of the world's flora. However, the accelerated destruction of botanically rich ecosystems has contributed to a gradual loss of native medicinal species. In previous study, we have observed a fast and intensive change in trade(More)
BACKGROUND/AIMS Leaves of Echinodorus macrophyllus (EM), from the Alismataceae family, have been used in Brazilian folk medicine for their anti-inflammatory and diuretic properties. In this work, the diuretic and nephroprotective activities of crude extracts of EM were evaluated. METHODS Normal Wistar rats were given 0.9% NaCl containing either EM (10-300(More)
For decades, several native medicinal species have been used by the pharmaceutical industry in Brazil to create commercial products. In 1995, the Ministry of Health, following the recommendations of the World Health Organization, established herbal regulations (RDC 17) in order to improve the quality of such products. In fact, only plant species with(More)
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