Gustavo Pelligra

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Herpes simplex virus encephalitis in the newborn typically involves the cerebral cortex in a widespread manner. Herpes simplex virus type 2 rarely involves the brainstem. Here we report a 16-day-old infant with predominant brainstem and cerebellar involvement secondary to herpes simplex virus type 2 infection. Diffusion-weighted MRI performed 3 days after(More)
Skeletal manifestations are the hallmark of the osteogenesis imperfecta group of disorders. Extraskeletal involvement may, however, contribute significantly to morbidity. Structural cardiovascular anomalies reported in osteogenesis imperfecta include aortic root dilatation and aortic and mitral valve dysfunction. Herein is reported the first case of(More)
To the Editor: We are thankful for the comments by Hakan et al. regarding our study [1]. Regarding the diagnosis of hypotension, we agree with that the diagnosis should not be based on the blood pressure reading alone. In the study we enroled newborns with Invasive mean blood pressure (MBP) <GA (Gestational Age) in 3 consecutive measurements that the(More)
OBJECTIVE The aim of the present retrospective study was to describe the use of nasal continuous positive airway pressure (NCPAP) and the prevalence of bronchopulmonary dysplasia (BPD). STUDY DESIGN Data from 1526 neonates with gestational age less than 32 weeks, admitted to Children's and Women's Health Centre of British Columbia (Vancouver, British(More)
We report a sick preterm neonate with a dramatic ileus presentation mimicking necrotizing enterocolitis that promptly reversed upon hydrocortisone supplementation. Because our case illustrates a previously unsuspected clinical visage of inadequate adrenal responses in sick preterm neonates, it also emphasizes the need for improved diagnostic algorithms to(More)
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