Gustavo Nobre

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The levels of resistance to nystatin induced in 16 strains of Torulospsis glabrata by a few subcultures in the presence of the drug were high (minimum inhibitory concentrations > 20 000 U ml-1) compared with those obtained in 12 strains of Candida albicans (minimum inhibitory concentrations less than or equal to 2000 U ml-1). The results suggest a high rate(More)
The majority of clinical isolates of T. glabrata has been shown highly sensitive to ketoconazole, when tested with an agar dilution method, and resistant, when using a broth dilution method. The fact was accounted for the high degree of mutation associated with the haploid state present in this species. Experimental T. glabrata infection in immunocompetent(More)
The sensitivity to 5-Fluorocytosine (5-FC) and the virulence for mice was assessed for 16 human isolates of Aspergillus: A. fumigatus 2, A. niger 7, A. flavus 4, A. terreus 2 and A. conicus (A. restrictus group) 1. Fourteen strains were recovered from ear exsudates, 1 from sputum and 1 from the pus of mastoid cells of an autopsy case with meningeal and(More)
Some of the characteristics of 42 clinical isolates of Haemophilus ducreyi are reported. Only six of the 42 strains were able to grow on horse-blood agar. All strains gave a positive oxidase test with tetramethyl-p-phenylenediamine and a negative result with dimethyl-p-phenylenediamine. All of 15 test strains were negative in the porphyrin test. Tests for(More)
Enhancement of Streptococcus faecalis infection and lowering of the complement level have been demonstrated in mice injected with a heat-treated suspension of baker's yeast (Saccharomyces cerevisiae). The leucocyte response to the infection was not affected. The yeast preparation showed, in vitro, an intense anti-complementary activity on mouse serum and(More)
Five strains of Cryptococcus neoformans isolated from the cerebro-spinal fluid and 4 from the blood of AIDS patients, were studied. Although morphologically identical, they differed in the auxanographic pattern. All strains were pathogenic for mice by intracerebral route. Six isolates were sensitive and the other three resistant to 5-fluorocytosine. All(More)
The results of an oxidase test were positive with species of Cryptococcus and eight species of Candida, but negative with Candida krusei and species of Saccharomyces and Torulopsis, grown on Columbia Agar base and similar media, including Brain Heart Infusion Agar and Mueller Hinton Agar. When grown on Sabouraud Dextrose Agar, all the yeast genera and(More)