Gustavo H. M. A. Rocha

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Rattus norvegicus as a model for persistent renal colonization by pathogenic Leptospira interrogans.

Daniel Abensur Athanazio, Everton Fagonde Silva, +5 authors Mitermayer G Reis
Acta tropica
2008

Leptospirosis continues to be a disease with a poorly understood pathogenesis. The experimental rat model is amenable for the investigation of leptospiral dissemination, tropism, persistence of renal… (More)

The flagellar attachment zone of Trypanosoma cruzi epimastigote forms.

Gustavo H. M. A. Rocha, Bruno Alves Brandão, Renato Arruda Mortara, Márcia Attias, Wanderley de Souza, Técia Maria Ulisses de Carvalho
Journal of structural biology
2006

The flagellar attachment zone (FAZ) is an adhesion region of Trypanosoma cruzi epimastigote forms where the flagellum emerges from the flagellar pocket and remains attached to the cell body. This… (More)

Artificial laminin polymers assembled in acidic pH mimic basement membrane organization.

Madalena Martins Sant'ana Barroso, Elisabete Freire, +5 authors Tatiana Coelho-Sampaio
The Journal of biological chemistry
2008

Natural laminin matrices are formed on cell membranes by a cooperative process involving laminin self-polymerization and binding to cognate cellular receptors. In a cell-free system, laminin can… (More)

Structural Changes of the Paraflagellar Rod during Flagellar Beating in Trypanosoma cruzi

Gustavo H. M. A. Rocha, Dirceu Esdras Teixeira, Kildare Miranda, Gilberto Weissmüller, Paulo Mascarello Bisch, Wanderley de Souza
PloS one
2010

BACKGROUND Trypanosoma cruzi, the agent of Chagas disease, is a protozoan member of the Kinetoplastidae family characterized for the presence of specific and unique structures that are involved in… (More)

Silver nanoparticle production by the fungus Fusarium oxysporum: nanoparticle characterisation and analysis of antifungal activity against pathogenic yeasts

Kelly Ishida, Talita Ferreira Cipriano, +4 authors Sonia Rozental
Memorias do Instituto Oswaldo Cruz
2014

The microbial synthesis of nanoparticles is a green chemistry approach that combines nanotechnology and microbial biotechnology. The aim of this study was to obtain silver nanoparticles (SNPs) using… (More)

Ultrastructure of Trypanosoma cruzi revisited by atomic force microscopy.

Gustavo H. M. A. Rocha, Kildare Miranda, Gilberto Weissmüller, Paulo Mascarello Bisch, Wanderley de Souza
Microscopy research and technique
2008

Most advances in atomic force microscopy (AFM) have been accomplished in recent years. Previous attempts to use AFM to analyze the organization of pathogenic protozoa did not significantly contribute… (More)

Attachment of flagellum to the cell body is important to the kinetics of transferrin uptake by Trypanosoma cruzi.

Gustavo H. M. A. Rocha, Sérgio Henrique Seabra, Kildare Rocha de Miranda, Narcisa L Cunha-E-Silva, Técia Maria Ulisses de Carvalho, Wanderley de Souza
Parasitology international
2010

The flagellar pocket and the cytostome are surface domains of Trypanosoma cruzi epimastigote involved in acquisition of nutrients. The cytostome is physically connected to the flagellar complex. To… (More)

Oral infection of mice with Fusobacterium nucleatum results in macrophage recruitment to the dental pulp and bone resorption

Lance A. Johnson, Cássio Luiz Coutinho Almeida-da-Silva, +6 authors David M. Ojcius
Biomedical journal
2018

BACKGROUND Fusobacterium nucleatum is a Gram-negative anaerobic bacterium associated with periodontal disease. Some oral bacteria, like Porphyromonas gingivalis, evade the host immune response by… (More)

The toxic effects of piperine against Trypanosoma cruzi: ultrastructural alterations and reversible blockage of cytokinesis in epimastigote forms

Leonardo Freire-de-Lima, Tatiana Santana Ribeiro, +7 authors Norton Heise
Parasitology Research
2008

In a previous work, we have investigated the effects of piperine and several of its chemical derivatives on the proliferation of the protozoan parasite Trypanosoma cruzi. It was observed that natural… (More)

Envelope lipid-packing as a critical factor for the biological activity and stability of alphavirus particles isolated from mammalian and mosquito cells.

Ivanildo P. Sousa, Carlos A M Carvalho, +4 authors Andre M O Gomes
The Journal of biological chemistry
2011

Alphaviruses are enveloped arboviruses. The viral envelope is derived from the host cell and is positioned between two icosahedral protein shells (T = 4). Because the viral envelope contains… (More)

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