Gurpreet S Sandhu

Learn More
Oxidized cellulose (Surgicel) has been used as a haemostatic agent in neurosurgery for five decades. Complications have been few. Two cases are reported of granulomatous reaction to oxidised cellulose two months and twelve months after removal of intracranial meningiomas. Both appeared as contrast enhancing space occupying lesions on CT scan and were taken(More)
BACKGROUND Synthetic vascular grafts cannot be used in small vessels because of graft failure caused by thrombosis and neointima formation. Rapid endothelialization may overcome this limitation. We hypothesized that a magnetic graft would be able to capture and retain endothelial cells labeled with paramagnetic particles. METHODS AND RESULTS Porcine blood(More)
OBJECTIVES/HYPOTHESIS To assess the results of primary endoscopic treatment of adult postintubation tracheal stenosis, to identify predictors of a successful outcome, and better define the scope and limitations of minimally-invasive surgery for this condition. METHODS Sixty-two consecutive patients treated between April 2003 and 2006 with initial(More)
OBJECTIVE To address questions about the etiology, behavior, optimal treatment, and prognosis of metastasizing pleomorphic adenoma (MPA), we undertook a review of the literature (1953-2005) and constructed a virtual series of all identified cases of MPA, metastatic lesions that are very occasionally identified in patients with a history of pleomorphic(More)
OBJECTIVE In patients with airway stenosis, anatomy of the lesion determines the magnitude of the biomechanical ventilatory disturbance and thus the nature and severity of symptoms. It also gives information about biology, likelihood of response to treatment, and prognosis of laryngotracheal lesions. Accurate airway sizing throughout treatment is therefore(More)
OBJECTIVE This article describes our initial clinical experience with time-resolved MR angiography (MRA) of the legs using the time-resolved imaging with stochastic trajectories (TWIST) technique with a half dose of gadolinium. MATERIALS AND METHODS Thirty-four patients underwent a TWIST examination of the legs at 3 T. Thirty-three patients also underwent(More)
OBJECTIVE/HYPOTHESIS The study's objective was to determine the utility of expiratory disproportion index (EDI), the ratio of forced expiratory volume in 1 second (FEV1) to peak expiratory flow rate (PEFR) (EDI = FEV1[L] /PEFR[L/s] × 100), in differentiating between laryngotracheal stenosis (LTS) and other respiratory diagnoses. LTS is an uncommon(More)
OBJECTIVES A novel method to magnetically localize endothelial cells at the site of a stented vessel wall was developed. The application of this strategy in a large animal model is described. BACKGROUND Local delivery of blood-derived endothelial cells has been shown to facilitate vascular healing in animal models. Therapeutic utilization has been limited(More)
OBJECTIVE The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction. METHODS AND RESULTS Coronary endothelial function was assessed in 490 patients between November 1993 and February 2007. Fasting lipids and nuclear(More)
BACKGROUND High sensitivity C-reactive protein (hsCRP) has been identified as a predictor of adverse cardiovascular outcomes. Whether hsCRP is a useful biomarker for risk stratification in contemporary percutaneous coronary intervention remains unknown. METHODS AND RESULTS We conducted a prospective study among 513 patients undergoing non-emergency(More)