Guresh Kumar

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OBJECTIVE The purpose of this study was to simultaneously evaluate multiple components of disequilibrium in patients with idiopathic Parkinson's disease (PD) in ON and OFF states and healthy age- and sex-matched controls on tests of balance, gait, and dynamometry. DESIGN Thirty subjects with Parkinson's disease and 30 controls were matched for age and(More)
Several single nucleotide polymorphisms of the TP53 gene have been reported, amongst which polymorphism in codon 72 (rs1042522) has received significant attention and shown to be associated with disease susceptibility in different cancer types. However, there are variable reports on this polymorphism in gliomas from worldwide with inconsistent results. In(More)
AIMS The aim was to study the effect of family history of type 2 diabetes mellitus (T2DM) on insulin sensitivity and β-cell function in normoglycemic offspring. MATERIAL AND METHODS Offspring of T2DM patients (cases) and individuals without family history of T2DM (controls) were the subjects for this cross-sectional study. All participants underwent 75 g(More)
Over 100,000 people commit suicide each year in India; yet, there has been limited micro-based study. This study marks the first study of suicide notes in India. The sample consisted of all available note-writers (n = 50), with a comparative sample of non-note writers (n = 50) of all suicides (n = 320, 16.47% of all postmortems) during a 1(1/2) year period(More)
BACKGROUND Intracerebral hemorrhage (ICH) is associated with high mortality and morbidity. Various clinical and imaging predictors of mortality have been observed in previous studies. AIMS To study factors associated with in-hospital mortality in patients with ICH and observe the disability status of patients [assessed by modified Rankin scale (mRS)] at(More)
OBJECTIVE To compare the efficacy of manual vacuum aspiration (MVA) with electric vacuum aspiration (EVA) and to evaluate whether cervical priming with misoprostol facilitates cervical dilation and reduces complications associated with first-trimester medical abortion performed up to 10 weeks of pregnancy. METHODS A total of 600 women who requested(More)
BACKGROUND There is no consensus on the role of cortisol in the pathogenesis of obesity and metabolic syndrome (MS). This cross-sectional study aimed to analyze the relationship of morning plasma cortisol and adrenocorticotropic hormone (ACTH) levels with body mass index (BMI) and glucose tolerance. SUBJECTS AND METHODS The sample frame was the "Offspring(More)
BACKGROUND AND OBJECTIVE There are sparse data regarding the impact of ventilator-associated pneumonia (VAP) on outcome among patients with chronic obstructive pulmonary disease (COPD) exacerbation. MATERIALS AND METHODS This retrospective study included patients with COPD exacerbation requiring endotracheal intubation for more than 48 h admitted in a(More)
BACKGROUND There is little published literature on the profile of patients with Cushing's syndrome (CS) from India. The aim of this study was to compile data of CS patients treated at this hospital. MATERIALS AND METHODS Patients referred to the endocrine services of this hospital for diagnosis/treatment of CS from January 1985 to July 2012 were the(More)
BACKGROUND & AIMS Patients with decompensated cirrhosis have significantly reduced survival without liver transplantation. Granulocyte colony-stimulating factor (G-CSF) has been shown to increase survival in patients with acute-on-chronic liver failure, and erythropoietin promoted hepatic regeneration in animal studies. We performed a double-blind,(More)