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Morbidity and Mortality of Laparoscopic Versus Open D2 Distal Gastrectomy for Advanced Gastric Cancer: A Randomized Controlled Trial.
TLDR
Experienced surgeons can safely perform LG with D2 lymphadenectomy for AGC, and the morbidity and mortality within 30 days after surgery between the LG and OG groups were compared on the basis of the modified intention-to-treat principle.
Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells
TLDR
It is demonstrated that the expression of circ-104916 is downregulated in GC tissues and cell lines, indicating that circ- 104916 was involved in the epithelial–mesenchymal transition process and might be a novel potential tumor suppressor and biomarker of GC.
The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer
TLDR
This guideline uses tables and is complemented by explanatory and descriptive notes covering the diagnosis, comprehensive treatment, and follow-up visits for gastric cancer in China.
Laparoscopic vs open D2 gastrectomy for locally advanced gastric cancer: a meta-analysis.
TLDR
Although a technically demanding and time-consuming procedure, LGD2 may be safe and effective, and offer some advantages over OGD2 for treatment of locally AGC.
Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer: The CLASS-01 Randomized Clinical Trial.
TLDR
Among patients with a preoperative clinical stage indicating locally advanced gastric cancer, laparoscopic distal Gastrectomy compared with open distal gastrectomy, did not result in inferior disease-free survival at 3 years.
ImmunoScore Signature: A Prognostic and Predictive Tool in Gastric Cancer
TLDR
The ImmunoScore (IS) could markedly improve the prediction of postsurgical survival and chemotherapeutic benefits in gastric cancer (GC) and complemented the prognostic value of the TNM staging system.
The roles of CT and EUS in the preoperative evaluation of gastric gastrointestinal stromal tumors larger than 2 cm
TLDR
CT features may be more useful than EUS features for predicting tumor mitotic index and, in addition, preoperative imaging features can help predict the prognosis of gastric GISTs.
Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis
TLDR
It is shown that colorectal cancer (CRC) derived exosomal miR-25-3p promotes vascular leakiness and angiogenesis, CRC metastasis, and is upregulated in CRC pateints with metastasis.
CircRNA_100269 is downregulated in gastric cancer and suppresses tumor cell growth by targeting miR-630
TLDR
The results suggest that circRNA_100269 and miR-630 comprise a novel pathway that regulates proliferation of GC cells.
Assessment of treatment options for rectosigmoid cancer: single-incision plus one port laparoscopic surgery, single-incision laparoscopic surgery, and conventional laparoscopic surgery
TLDR
RPLS for rectosigmoid cancer is feasible, with short-term safety and long-term oncological safety comparable to that of CLS, and SILS + 1 is a better choice than CLS or SILS for recto-sonic cancer because it minimizes invasiveness and reduces technical difficulties.
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