Guosheng Huang

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The epidermis is a dynamic renewing structure that provides life-sustaining protection from the environment. The major cell type of the epidermis, the epidermal keratinocyte, undergoes a carefully choreographed program of differentiation. Alteration of these events results in a variety of debilitating and life-threatening diseases. Understanding how this(More)
The forkhead transcription factor hepatocyte nuclear factor 3beta (HNF3beta) is essential in foregut development and the regulation of lung-specific genes. HNF3beta expression leads to growth arrest and apoptosis in lung cancer cells and HNF3beta is a candidate tumor suppressor in lung cancer. In a transcriptional profiling study using a conditional cell(More)
An efficient method for the Pd-catalyzed regioselective C-2 arylation of quinolines is presented. Reactions of various substituted quinolines and unactivated arenes have been conducted under mild conditions. The result shows good product yields of 2-arylquinolines, which are highly useful building blocks for the synthesis of bioactive alkaloid natural(More)
We investigate the effects of 20-hydroxyecdysone (20E) on improving memory deficits in the current study by using an animal model of type 1 diabetes mellitus in rats. Animals in control group went on a normal diet. Rats that developed diabetes were divided into 4 groups, including STZ-induced diabetic group which was treated with saline and three 20E groups(More)
In order to support the QoS of the network, a scalable framework based on the deterministic QoS guarantees was proposed. On the basis of the edge-core network model, we introduced the notion of flow and micro-flow, a two-layer scheduling model based on the arrival curves and service curves, and derived the upper bound on the queue length, the queue delay,(More)
Energy is one of the most important resources in wireless sensor networks. Recently, the mobility of base station has been exploited to preserve the energy. But in event driven networks, the mobility issue is quite different from the continuous monitoring one because only a small portion of sensor node has data to send at one time. The number of sensor node(More)
Cold spraying is a promising method for rapid prototyping due to its high deposition efficiency and high-quality bonding characteristic. However, many researchers have noticed that holes cannot be replenished and will grow larger and larger once formed, which will significantly decrease the deposition efficiency. No work has yet been done on this problem.(More)
A novel iodine-mediated oxidative tandem cyclization reaction of simple enaminones has been developed for the synthesis of substituted furopyridines through C-C/C-N/C-O bond formation in a one-pot procedure. Substituted furopyridines are obtained in moderate to good yield. In addition, I- and Br-substituted furopyridines have been successfully produced by(More)
An efficient method for the direct synthesis of substituted quinolines from anilines and aldehydes through C-H functionalization, C-C/C-N bond formation, and C-C bond cleavage has been developed. The method is simple and practical and employs air as an oxidant.