Guoqiang Niu

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OBJECTIVE By using the cell wall component of Mycobacterium tuberculosis 19 000 lipoprotein (P19) and curcumin (CUR) acting on the human macrophage cell line WBC264-9C, and by the blocking of the p38 mitogen-activated protein kinases (p38 MAPK) signaling pathway, we wanted to investigate the effect of curcumin on P19-induced inflammatory responses and(More)
Mycobacterium tuberculosis (M.tb) enhances its survival in macrophages by suppressing immune responses, in part through its complex cell wall structures. M.tb 19‑kDa lipoprotein (P19), a component of the complex cell wall structures of M.tb, is a Toll‑like receptor (TLR) agonist, and may induce immune responses through TLR2. Furthermore, the activation of(More)
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