Guoqiang Liang

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BACKGROUND Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed tumors worldwide and is known to be resistant to conventional chemotherapy. New therapeutic strategies are urgently needed for treating HCC. Osthole, a natural coumarin derivative, has been shown to have anti-tumor activity. However, the effects of osthole on HCC have not yet(More)
—A simple PS adaptive integral sliding mode controller is designed for the pitch channel linear model of supersonic missile firstly. In order to improve the performance of the proposed method, two improvements also proposed. Finally, a hybrid PISS adaptive control is formed which contains proportion control, integration control, the sign function adn soft(More)
3-Deoxyglucosone (3DG), a highly reactive dicarbonyl intermediate generated during glycation, has been confirmed to be markedly elevated in the plasma of patients with diabetes. Our previous study found that there is an association between increasing accumulation of plasma 3DG and impaired glucose regulation in non-diabetic seniors (females, >50 years old;(More)
Osthole, a natural coumarin derivative, has been shown to have anti-tumor and anti-inflammatory activity. However, the effect of osthole on anti-tumor immune responses in tumor-bearing mice has not yet been reported. In the present study, osthole treatment did not affect the weight and the coefficient of thymus and spleen in tumor-bearing mice with(More)
Considering pitch channel simplified model of missile control system, a VSCL(variable structure control law) is designed by using overload and angle velocity signals. Especially, an analysis is proposed for the situation of equal control with uncertainties. An integral action is introduced to compensate the uncertainties and a soft function is adopted to(More)
The overload control of missile system is researched under the condition that the control direction is unknown. A nussbaum gain strategy is adopted to solve the unknown control direction problem for the linear model of missile motion of pitch channel. The backstepping technology and integral action are used to cope the system uncertainty. A novel type of(More)