Guokuan Li

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Melanoma development not only involves genetic and epigenetic changes that take place within the cell, but also involves processes determined collectively by micro-environmental factors, including cell-cell interactions and communications. During the transition from normal cells to benign and malignant lesions, and subsequently to metastatic cancer,(More)
Common carotid artery intima-media thickness (IMT), which is usually measured upon ultrasound images, is an important indicator to cardiovascular diseases. This paper proposes a snake model based segmentation method to automatically detect the boundary of intima-media for IMT measurement. In the proposed method, two contours are initialized from line(More)
Signal changes observed in high-resolution in vivo magnetic resonance (MR) images acquired during cerebral ischemia in small animal models must be correlated to molecular indicators of tissue damage obtained from digitized histological brain sections. An effective image registration technique that incorporates both a linear and non-linear thin plate spline(More)
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