Guocheng Zhang

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OBJECTIVE : The objective of this study was to investigate the prevalence of sexually transmitted diseases (STDs), including HIV infection, and sexual risk behaviors among men who have sex with men (MSM) in Jiangsu Province, China. DESIGN : The authors conducted a cross-sectional study. METHODS : From February to July 2003, men who attended 10(More)
AIMS Fetal hypoxic-ischemic brain injury (HIBI) is a severe condition for which no effective therapy exists. In this study mesenchymal stem cells (MSCs) from human umbilical cord blood (UCB) of full-term newborns were isolated and intracerebrally transplanted into rat neonates after HIBI induction. Nerve function was assessed by the modified neurological(More)
OBJECTIVES To evaluate the dental health status and treatment needs of people affected by leprosy in China, and provide a basis for the development of national or regional dental health programmes to cover the treatment needs of this population. DESIGN A cross-sectional study with 613 former leprosy patients was carried out in six leprosy villages, in(More)
Nanoparticles are regarded as promising carriers for targeted drug delivery and imaging probes. A fundamental understanding of the dynamics of polymeric nanoparticle targeting to receptor-coated vascular surfaces is therefore of great importance to enhance the design of nanoparticles toward improving binding ability. Although the effects of particle size(More)
As a common human pathogen, parvovirus B19 (B19V) has been shown to be associated with many heart diseases, such as myocarditis, cardiomyopathy and cardiopericarditis. The virus protein 1-unique region (VP1u) is critical to B19V infectivity, but its role in the pathogenesis of B19V-induced myocardial injury has not been well studied. In this study to(More)
OBJECTIVE To Study the incidence and clinical characteristics of dapsone hypersensitivity syndrome (DHS) among MDT-treated leprosy patients from 2006 to 2009 in China. METHODS A retrospective survey was carried out throughout China using a specially designed questionnaire. RESULTS From 2006 to 2009, there were 63 new patients reported to have DHS with(More)
BACKGROUND Infection with parvovirus B19 (B19) was reported to be correlated with myocarditis, cardiomyopathy, and kawasaki disease. But no information is available about the relationship between inutero B19 infection and congenital heart disease (CHD). OBJECTIVE To explore whether there is relationship between B19 infection and CHD. STUDY DESIGN(More)
OBJECTIVE This study was conducted to evaluate the effectiveness of uniform multi-drug therapy (UMDT) in patients with multibacillary (MB) leprosy. METHODS Newly detected MB leprosy patients were treated with six months of UMDT as recommended by the World Health Organization (WHO). The effectiveness of treatment was evaluated by clinical status and skin(More)
The processes that structure assemblages of species in hyper-diverse genera, such as Ficus (Moraceae), are not well understood. Functional diversity of co-occurring species can reveal evidence for assembly processes; however, intraspecific variation may weaken species-level patterns. We studied whether functional and phylogenetic diversity of Ficus species(More)