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Four new benzofurans from seeds of Styrax perkinsiae.
TLDR
Four new benzofurans trans-5-(3-hydroxypropyl)-7-methoxy-2-[2,3-dihydro-3-Hydroxymethyl-7- meth oxygen-2-(3,4-methylenedioxyphenyl)-benzofuran-5-yl]benz ofuran exhibited cytotoxic activity in vitro using two breast cancer cell lines MCF-7 and MDA-MB-231. Expand
Chaetocochins A-C, epipolythiodioxopiperazines from Chaetomium cochliodes.
Three new epipolythiodioxopiperazines, chaetocochins A (1), B (2), and C (3), along with dethio-tetra (methylthio) chetomin (4) and chetomin (5), were isolated from the ethyl acetate extract of theExpand
Sesterterpenoids, terretonins A-D, and an alkaloid, asterrelenin, from Aspergillus terreus.
Four new sesterterpenoids, terretonins A-D (1-4), and a new alkaloid, asterrelenin (5), together with five known compounds, were isolated from the ethyl acetate extract of a solid-state fermentedExpand
Inhibitory effect of luteolin on estrogen biosynthesis in human ovarian granulosa cells by suppression of aromatase (CYP19).
TLDR
It is found that the dietary flavonoid luteolin potently inhibited estrogen biosynthesis in a dose- and time-dependent manner in KGN cells derived from human ovarian granulosa cells, the major source of estrogens in premenopausal women. Expand
Two new alkaloids from Melodinus hemsleyanus Diels
Two new monoterpenoid indole alkaloids, named 14,15-dihydro-14β,15β-epoxy-10-hydroxyscandine (1) and 15α-hydroxy-meloscandonine (2), together with 12 known compounds, were isolated from the aerialExpand
Novel stilbenes from Artocarpus nanchuanensis
Four new stilbene derivatives, hypargystilbenes B-E (1–4), together with seven known compounds (5–11), were isolated from the stems of Artocarpus nanchuanensis S.S. Chang. Their structures wereExpand
Bioactive steroidal alkaloids from the fruits of Solanum nigrum.
TLDR
Solanine A showed the most potent inhibitory activity against the LPS-induced NO production in murine RAW264 and also showed significant cytotoxicity against MGC803, HepG2 and SW480 cancer cell lines with IC50 values of 6.00 ±-0.52 μM, 9.25 ± 0.49 μT, respectively. Expand
Flavonoid glycosides and alkaloids from the embryos of Nelumbo nucifera seeds and their antioxidant activity.
Chemical investigation of the embryos of Nelumbo nucifera afforded four new flavone C-glycosides, named nelumbosides A-D (1-4), together with nine known ones, comprising five flavonoids (5-9) andExpand
Steroidal saponins from Myriopteron extensum and their cytotoxic activity.
TLDR
Two new steroidal saponins were isolated from the whole plants of Myriopteron extensum (Wight) and exhibited significant cytotoxicity against eight cancer cell lines with a mean GI value of 0.346 microg/mL. Expand
Brevianamide J, a new indole alkaloid dimer from fungus Aspergillus versicolor.
TLDR
Brevianamide J, a new indole alkaloid dimer, was isolated together with four new diketopiperazine alkaloids from the solid-state fermented culture of Aspergillus versicolor and X-ray crystallographic analysis confirmed the structures of 1 and 4. Expand
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