Myeloid-derived suppressor cells (MDSCs) play an important role in impairing the function of T cells. We characterized MDSCs in two chronic hepatitis C (CHC) cohorts: a cross-sectional group that included 61 treatment-naive patients with CHC, 14 rapid virologic response (RVR) cases and 22 early virologic response (EVR) cases; and a longitudinal group of 13… (More)
This paper presents a swirl-shaped microfeatured ionic polymer-metal composite (IPMC) actuator. A novel micromachining process was developed to fabricate an array of IPMC actuators on a glass substrate and to ensure that no shortcircuits occur between the electrodes of the actuator. We demonstrated a microfluidic scheme in which surface tension was used to… (More)
This paper presents a novel biomimetic robotic arm for dynamic curvature/haptic detection with self-power generation function. The soft robotic arm is fabricated with an ionic polymer metal composite (IPMC) material and integrated with a functionalized piezoelectric polyvinylidene fluoride (PVDF) film. This device performs curvature and haptic sensing using… (More)
A compact, low-cost, low power consumption wireless sensor system aiming at ball screws monitoring is proposed in this work. The temperature rise and vibration are monitored during machine operation. Those data can be used to diagnose the health status of the feed drive, leading to an intelligent manufacture.
This paper presents an innovative tuning fork-shaped ionic polymer metal composite (IPMC) actuator. With an integrated soft strain gauge and water supply mechanism (WSM), the surface strain of the actuator can be sensed in situ, and providing a continuous water supply maintains the water content inside the IPMC for long-term operation in air. The actuator… (More)
This paper presents the microfabrication of an acoustic impedance gradient matching layer on a spherically-shaped piezoelectric ultrasonic transducer. The acoustic matching layer can be designed to achieve higher acoustic energy transmission and operating bandwidth. Also included in this paper are a theoretical analysis of the device design and a… (More)