Learn More
Aim:To develop and evaluate a whole-body physiologically based pharmacokinetic (WB-PBPK) model of bisoprolol and to simulate its exposure and disposition in healthy adults and patients with renal(More)
Heart failure is associated with impaired cardiac output and tissue perfusion, thereby resulting in altered drug disposition and exposure [1–4]. In a recent issue of Clinical Pharmacokinetics, Rasool(More)