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PURPOSE To assess cancer detection rates, false-positive rates before arbitration, positive predictive values for women recalled after arbitration, and the type of cancers detected with use of digital mammography alone and combined with tomosynthesis in a large prospective screening trial. MATERIALS AND METHODS A prospective, reader- and modality-balanced(More)
BACKGROUND Digital breast tomosynthesis (DBT) is a promising new technology. Some experimental clinical studies have shown positive results, but the future role and indications of this new technique, whether in a screening or clinical setting, need to be evaluated. PURPOSE To compare digital mammography and DBT in a side-by-side feature analysis for(More)
To compare double readings when interpreting full field digital mammography (2D) and tomosynthesis (3D) during mammographic screening. A prospective, Ethical Committee approved screening study is underway. During the first year 12,621 consenting women underwent both 2D and 3D imaging. Each examination was independently interpreted by four radiologists under(More)
The germination of the pollen grains and the growth rate of the pollen tubes of eight mutants of Pisum sativum were compared with the parent line by in vitro investigations. All of the mutants studied showed a retardation of pollen tube growth as compared to the parent line, resulting in competitive elimination of some of the gametes in plants heterozygous(More)
BACKGROUND Double reading improves the cancer detection rate in mammography screening. Single reading with computer-aided detection (CAD) has been considered to be an alternative to double reading. Little is known about the potential benefit of CAD in breast cancer screening with double reading. PURPOSE To compare prospective independent double reading of(More)
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