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In this paper, we discuss the properties of biological data and challenges it poses for data management, and argue that, in order to meet the data management requirements for 'digital biology', careful integration of the existing technologies and the development of new data management techniques for biological data are needed. Based on this premise, we(More)
BACKGROUND Kyoto Encyclopedia of Genes and Genomes (KEGG) is an online and integrated molecular database for several organisms. KEGG has been a highly useful site, helping domain scientists understand, research, study, and teach metabolisms by linking sequenced genomes to higher level systematic functions. KEGG databases are accessible through the web pages(More)
A metabolic network describes how different cellular processes (i.e., pathways) are connected and work together as part of a metabolism. The complexity of metabolisms and their working principles increase dramatically in higher order organisms (e.g., mammalians) in comparison to relatively lower level organisms (e.g., prokaryotes). As the complexity(More)
In this work we compare and contrast proposed techniques and experiments in the subdomain of radiology text classification. In the past, systems have relied on two main approaches: rule-based or natural language processing plus machine learning (NLP/ML). Simple rule-based approaches have demonstrated great efficacy, at the high cost of requiring medical(More)
The Bulletin of the Technical Committee on Data Engineering is published quarterly and is distributed to all TC members. Its scope includes the design, implementation , modelling, theory and application of database systems and their technology. Letters, conference information, and news should be sent to the Editor-in-Chief. Papers for each issue are(More)
Extending relational algebra and rela-tional calculus with set-valued attributes and aggregate functions, ACM Transac-a tuple t in I, produces the output of the query on I ? ftg. Then both proofs in 9] show how to use this assumption to produce an expression in rst-order logic plus g that computes the transitive closure of a chain. Since the construction of(More)
Comparing and identifying matching metabolites, reactions, and compartments in genome-scale reconstructed metabolic networks can be difficult due to inconsistent naming in different networks. In this paper, we propose metabolite and reaction matching techniques for matching metabolites and reactions in a given metabolic network to metabolites and reactions(More)
note: With the exception of the last pages –which would be the back cover of the printed issue– that are not included in this file, it has the same contents as the printed edition. All the articles are also available individually online and have been put together here for convenience only.] SIGMOD Record SIGMOD Record is a quarterly publication of the(More)