Guiseppe Ciccotosto

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Alzheimer s disease (AD) is an age-related neurodegenerative disease. Its pathological indicators include extracellular amyloid plaques, the main constituent of which is the amyloid b-peptide (Ab), and neurofibrillary tangles composed of hyperphosphorylated tau protein. Current evidence suggests that the aggregation of Abs drives the disease process, as(More)
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