Guillermo Narváez

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Oxygen delivery (DO2) and related variables were studied in eight dogs during severe untreated peritonitis induced by cecal ligation and perforation. The development of peritonitis was accompanied by abdominal fluid sequestration and significant increases in hemoglobin (Hgb), arterial oxygen content (CaO2), and P50. Changes in mixed venous PO2 (P-vO2),(More)
INTRODUCTION Mathematical models that correlate chemical structure with biological activity have been useful in the design of new drugs and can be used to predict biological behavior of new, chemically related molecules. OBJECTIVES A mathematical model was generated to correlate the substrate affinities with variations in the molecular topology of glycine(More)
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