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Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction

• Mateusz Pawel Poltorak, Rémy Sadoul, Guillermo Keilhauer, Carla Landa, Thomas Fahrig, Maja K. Schachner
• The Journal of cell biology
• 1987

A monoclonal antibody to the myelin-associated glycoprotein (MAG) was prepared and characterized to probe for the involvement of MAG in cell surface interactions among neural cells in vitro. The… (More)

Differential inhibition of neurone-neurone, neurone-astrocyte and astrocyte-astrocyte adhesion by L1, L2 and N-CAM antibodies.

• Guillermo Keilhauer, Andreas Faissner, Maja K. Schachner
• Nature
• 1985

The cell adhesion molecules L1, N-CAM and Ng-CAM have been implicated in cell-cell interactions among developing neural cells. L1 and N-CAM are structurally and functionally distinct molecular… (More)

Biosynthesis and membrane topography of the neural cell adhesion molecule L1.

• Andreas Faissner, David B Teplow, Daniel Kuebler, Guillermo Keilhauer, Vera Kinzel, Maja K. Schachner
• The EMBO journal
• 1985

The biosynthesis and membrane topography of the neural cell adhesion molecule L1 have been studied in cerebellar cell cultures by metabolic labeling and immunoprecipitation. Pulse and pulse-chase… (More)

The J1 glycoprotein--a novel nervous system cell adhesion molecule of the L2/HNK-1 family.

• J. Kruse, Guillermo Keilhauer, Andreas Faissner, Rupert Timpl, Maja K. Schachner
• Nature
• 1985

The neural cell adhesion molecules L1 and N-CAM share a common carbohydrate epitope that is recognized by the monoclonal antibodies L2 and HNK-1. The L2/HNK-1 epitope is also present on the… (More)

The L2/HNK-1 carbohydrate of neural cell adhesion molecules is involved in cell interactions

• V Künemund, Firoze B. Jungalwala, G. Fischer, Dean Chou, Guillermo Keilhauer, Maja K. Schachner
• The Journal of cell biology
• 1988

We investigated whether the L2/HNK-1 carbohydrate epitope, expressed by two unusual glycolipids and several neural adhesion molecules, including L1, neural cell adhesion molecule, J1, and the… (More)

Benzimidazo[1,2-c]quinazolines: a new class of antitumor compounds.

• Miguel F Braña, Juan Manuel Castellano, +5 authors Nigel J. Walker
• Anti-cancer drug design
• 1994

A series of substituted benzimidazo[1,2-c]quinazolines have been synthesized. This class of compound has been designed by structural comparison with other intercalator patterns. The determination of… (More)

Reversal of multi-drug resistance in human KB cell lines by structural analogs of verapamil.

• Robert Pirker, Guillermo Keilhauer, Manfred Raschack, Christian Lechner, H. Ludwig
• International journal of cancer
• 1990

Several structural analogs of verapamil were studied for their ability to reverse multi-drug resistance (MDR) in human KB cell lines. D595, D792 and verapamil completely reversed resistance to… (More)

Comparison of astrocytic morphology, proliferation, marker profile and response to neurons in wild-type and weaver mutant mouse cerebella in culture.

• G. Fischer, Guillermo Keilhauer, Maja K. Schachner
• Brain research
• 1986

In serum-free monolayer cultures of early postnatal weaver (wv/wv) cerebellum granule neurons show decreased attachment, survival and neurite outgrowth when compared to wild-type (+/+) littermate… (More)

Astrocytes support incomplete differentiation of an oligodendrocyte precursor cell.

• Guillermo Keilhauer, Dimitri Meier, S Kuhlmann-Krieg, Jens Nieke, Maja K. Schachner
• The EMBO journal
• 1985

Glial fibrillary acidic protein-positive astrocytes, but not neurons or fibroblasts, support the differentiation of an oligodendroglial precursor cell expressing O4 antigen and vimentin into an O4… (More)

Neuronal influence on antigenic marker profile, cell shape and proliferation of cultured astrocytes obtained by microdissection of distinct layers from the early postnatal mouse cerebellum.

• Itsuki Nagata, Guillermo Keilhauer, Maja K. Schachner
• Brain research
• 1986

To study the cellular heterogeneity of astrocytes from early postnatal mouse cerebellum in culture, Bergmann glia were enriched by hand-dissection of Purkinje, molecular and external granular layers… (More)

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