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  • J Escoffier, Sandra Yassine, +11 authors Christophe Arnoult
  • Biology, Medicine
  • Molecular human reproduction
  • 2015 (First Publication: 1 February 2015)
  • We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia (70%) and described that Dpy19l2 knockout (KO) mice faithfully reproduce the human phenotype ofExpand
  • Virginie Pierre, Guillaume Martinez, +7 authors Christophe Arnoult
  • Medicine, Biology
  • Development
  • 2012 (First Publication: 15 August 2012)
  • Sperm-head elongation and acrosome formation, which take place during the last stages of spermatogenesis, are essential to produce competent spermatozoa that are able to cross the oocyte zonaExpand
  • Clémentine Wambergue, Raoudha Zouari, +14 authors Charles Coutton
  • Biology, Medicine
  • Human reproduction
  • 2016 (First Publication: 1 June 2016)
  • STUDY QUESTION Does DNAH1 status influence intracytoplasmic sperm injection (ICSI) outcomes for patients with multiple morphological abnormalities of the sperm flagella (MMAF)? SUMMARY ANSWERExpand
  • J Escoffier, Hoi Chang Lee, +13 authors Christophe Arnoult
  • Biology, Medicine
  • Human molecular genetics
  • 2016 (First Publication: 1 March 2016)
  • In mammals, sperm-oocyte fusion initiates Ca(2+) oscillations leading to a series of events called oocyte activation, which is the first stage of embryo development. Ca(2+) signaling is elicited byExpand
  • Leyla Ounis, Abdelali Zoghmar, +11 authors Pierre F Ray
  • Medicine
  • Asian journal of andrology
  • 2015 (First Publication: 22 August 2014)
  • Klinefelter syndrome and Y-chromosomal microdeletion analyses were once the only two genetic tests offered to infertile men. Analyses of aurora kinase C (AURKC) and DPY19L2 are now recommended forExpand
  • Sandra Yassine, J Escoffier, +10 authors Christophe Arnoult
  • Medicine, Biology
  • Molecular human reproduction
  • 2015 (First Publication: 1 February 2015)
  • We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia. Non-genetically characterized cases of globozoospermia were associated with DNA alterations, suggestingExpand
  • Zine-eddine Kherraf, Amir Amiri-Yekta, +23 authors Pierre F Ray
  • Biology, Medicine
  • American journal of human genetics
  • 2018 (First Publication: 6 September 2018)
  • Multiple morphological abnormalities of the sperm flagellum (MMAF) is a severe form of male infertility defined by the presence of a mosaic of anomalies, including short, bent, curled, thick, orExpand