Guillaume Coindard

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INTRODUCTION AND OBJECTIVES The pattern of arachidonate acid (AA) transformation in tumor cells has been shown to play a role in determining tumor cell invasiveness. AA is released from membrane phospholipids by cPLA(2). Then it is metabolized into prostaglandins and PGE(2) especially via cyclooxygenase pathways. PGE(2) production seems to be necessary for(More)
BACKGROUND France's ethical and legal principles place general practitioners (GPs) at the forefront of cancer patient management, coordination, and follow-up. The objective of this study was to determine the actual role of GPs in the follow-up phase as well as patient perspectives on their GPs. METHOD A multidisciplinary group of researchers conducted(More)
BACKGROUND Primary care physicians (PCPs) play a key role regarding vaccination in France. The aims of the present study were to define the scoring rules and to assess the measurement properties of the 'Determinants of Intentions to Vaccinate' (DIVA©) questionnaire that aims to assess PCPs' attitudes and beliefs toward vaccination. METHODS The DIVA(More)
The new swine-origin influenza A (H1N1) strain (S-OIV) pandemia may expose immunodepressed cancer patients under chemotherapy to an increased risk of mortality. Here, we put into perspective available antiviral treatments and influenza vaccination efficacy in cancer patients and consider that recommendations for seasonal influenza vaccination for these(More)
OBJECTIVES Vaccination is an effective way to reduce morbidity and mortality related to infectious diseases. In France, primary care physicians are the main administrators of vaccines. Our objective was to conduct an exploratory qualitative study with primary care physicians to identify determinants of their commitment to vaccination. METHODS A(More)
OBJECTIVE Based on patient's declarations, evaluate if the media coverage of the pandemic flu (H1N1) has lead to an overconsumption of primary care. Identify the opinions of the general practionners (GP) concerning this media coverage and the health crisis. METHODS A prospective study, based on an electronic questionnaire, was conducted during the main(More)
Competing interest LM is an expert consultant for Amgen Inc., AstraZeneca Pharmaceuticals, Lilly, Ipsen, Mayoly Spindler, MSD, Novo Nordisk, Pfizer, Sanofi, Sanofi Pasteur MSD and Servier. DD is a consultant for Abbvie, BMS, Novartis, Novo Nordisk, Pfizer and Sanofi. FD participates in working groups and attends conferences at the request of Pfizer, GSK and(More)
Medical oncology, which post-graduate diploma was established in France in 1984, was built on the practice of anticancer chemotherapy and interdisciplinarity. The political impetus of the Cancer Plan 2009-2013 had helped develop and generalize its learning since 2011. These recent changes explain the lack of information we have on the socialization of young(More)
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