Guillaume Brotons

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We have investigated the x-ray scattering signal of highly aligned multilayers of the zwitterionic lipid 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine containing pores formed by the antimicrobial peptide alamethicin as a function of the peptide/lipid ratio. We are able to obtain information on the structure factor of the pore fluid, which then yields the(More)
We investigated the structure of the hydrophobic domain of the severe acute respiratory syndrome E protein in model lipid membranes by x-ray reflectivity and x-ray scattering. In particular, we used x-ray reflectivity to study the location of an iodine-labeled residue within the lipid bilayer. The label imposes spatial constraints on the protein topology.(More)
The agent responsible for the recent severe acute respiratory syndrome (SARS) outbreak is a previously unidentified coronavirus. While there is a wealth of epidemiological studies, little if any molecular characterization of SARS coronavirus (SCoV) proteins has been carried out. Here we describe the molecular characterization of SCoV E protein, a critical(More)
The ternary phase diagram of the amphiphilic triblock copolymer PEO-PPO-PEO ((EO)(20)(PO)(70)(EO)(20) commercialized under the generic name P123), water, and ethanol has been investigated at constant temperature (T = 23 degrees C) by small-angle X-ray scattering (SAXS). The microstructure resulting from the self-assembly of the PEO-PPO-PEO block copolymer(More)
In this review article we discuss the thin film analytical techniques of interface sensitive X-ray and neutron scattering applied to aligned stacks of amphiphilic bilayers, in particular phospholipid membranes in the fluid L(alpha) phase. We briefly discuss how the structure, composition, fluctuations and interactions in lipid or synthetic membranes can be(More)
Using x-ray photon correlation spectroscopy, we studied the layer fluctuations in the lamellar phase of an ionic lyotropic system. We measured the relaxation rate of in-plane (undulation) fluctuations as a function of the wave vector. Static and dynamic results obtained during the same experiment were combined to yield the values of both elastic constants(More)
This paper reports an experimental study of a homogeneous nucleation process in the direct space, using an atomic-force microscope. Nucleated patterns are holes in a thin diblock copolymer film. The formation of nuclei from the metastable majority phase is followed either by the dissolution or by the growth of the hole. It is also preceded by the unexpected(More)
There has been an intense research effort in the last decades in the field of biofouling prevention as it concerns many aspects of everyday life and causes problems to devices, the environment, and human health. Many different antifouling and antimicrobial materials have been developed to struggle against bacteria and other micro- and macro-organism(More)
Charged surfactant bilayers deposited in thick multilayer films and swollen in vapor or in solution have been studied by coherent x-ray reflectivity. We report a pronounced static speckle pattern which persists under conditions of full hydration, despite the fact that the bilayers are fluid, relatively soft, and consisting of soluble amphiphiles (DDABr).(More)
The effect of dynamic arm exchange on the crystallization and the jamming of multiarm starlike polymers was studied using small angle x-ray scattering and rheology. Poly(ethylene oxide) end capped with a small hydrophobic chain formed spherical micelles in water. Dynamic arm exchange allowed rapid crystallization and caused a discontinuous liquid-solid(More)