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Infiltration and local proliferation are known factors that contribute to tubulointerstitial macrophage accumulation. This study explored the time course of these two contributors' roles as tubulointerstitial inflammation and fibrosis progressing, and evaluated the mechanisms of the protective effect of atorvastatin. Unilateral ureteral obstructive (UUO)(More)
BACKGROUND Lipid abnormalities may play a role in the progression of nephrosis. Recent studies have demonstrated that oxidized low-density lipoprotein (oxLDL) appears to be a detrimental factor for the glomerular mesangium and podocytes. The aim of the present study is to identify the potential effects of oxLDL on tubular epithelial cells (TECs) in vitro(More)
Asiri S. Abeyagunawardena Carolyn L. Abitbol Peter Abt Gian Luigi Adani Raymond D. Adelman Dwomoa Adu Rekha Agrawal Sarah W. Alexander Steven R. Alexander Uri S. Alon Dominik M. Alscher Amira Al-Uzri Ofelia Alvarez Kerstin Amann Alessandro Amore John M. Andersen Nigel G. Anderson Sharon Anderson Jean-Luc André Sharon Andreoli Styliani Andronikou Franca(More)
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