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Comparing Pioglitazone to Insulin with Respect to Cancer, Cardiovascular and Bone Fracture Endpoints, Using Propensity Score Weights
BackgroundDiabetes is an important global disease, associated with significant morbidity and an increased risk of death due to chronic end-organ complications. The thiazolidinediones, used mainly asExpand
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Benefit–Risk Assessment of Blinatumomab in the Treatment of Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia
Blinatumomab is the first-and-only Food and Drug Administration (FDA)-approved cluster of differentiation (CD) 19-directed CD3 bispecific T-cell engager (BiTE®) immunotherapy. It is currently FDAExpand
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G2 cell cycle arrest and cyclophilin A in lentiviral gene transfer.
Lentiviral vectors derived from the human immunodeficiency virus-1 (HIV-1) have a higher propensity to transduce nondividing cells compared to vectors based on oncoretroviruses. We report here thatExpand
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Increased Risk of Subsequent Myocardial Infarction in Patients With Type 2 Diabetes: A Retrospective Cohort Study Using the U.K. General Practice Research Database
OBJECTIVE To compare the risk of subsequent myocardial infarction (MI) between patients with and without type 2 diabetes mellitus (T2DM) in a retrospective cohort study. RESEARCH DESIGN AND METHODSExpand
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Metastatic colon cancer to the testicle presenting as testicular hydrocele.
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A comparison of all-cause mortality with pioglitazone and insulin in type 2 diabetes: an expanded analysis from a retrospective cohort study
Abstract Objectives: The objectives of this study were to assess and compare all-cause mortality rates between pioglitazone (PIO) and insulin (INS). Research design: The study population includedExpand
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94. Transgene Expression with Integration-Deficient HIV-1 Based Lentiviral Vectors Expressing Class I Integrase Mutants
Despite the benefit of achieving stable transgene expression with retroviral-based vectors, adverse effects associated with the administration of these vectors include the potential for insertionalExpand