• Publications
  • Influence
Mitochondrial and energy metabolism‐related properties as novel indicators of lung cancer stem cells
Energy metabolism is the foundation of survival for all organisms, and mitochondria are the most important energy‐supplying organelles in eukaryotic cells. However, the mitochondrial andExpand
  • 129
  • 8
Effect of TGF-beta 1 on PDGF receptors expression in human scar fibroblasts.
This study examined the effect of exogenous TGF -beta1 on platelet derived growth factor alpha and beta (PDGF-alpha, beta) receptor expression in human dermal fibroblasts derived from both normalExpand
  • 32
  • 2
Heterogeneity of Mitochondrial Membrane Potential: A Novel Tool to Isolate and Identify Cancer Stem Cells from a Tumor Mass?
It is believed that cancer stem cells (CSCs) are precursors for the formation, development, and recurrence of malignant tumors. However, it has proven difficult to isolate and enrich these rare,Expand
  • 30
  • 2
Enhancement of Antiangiogenic Effects of Human Canstatin with a Hypoxia‐Regulated Transgene Vector in Lung Cancer Model
Canstatin, a newly identified antiangiogenesis protein, has a potent inhibitory effect on the proliferation and growth of en-dothelial cells. To enhance the expression and antiangiogenic effects ofExpand
  • 15
  • 1
[Study on association between CC16 gene G38A mutation and asthma in the patients of Han population in Chongqing, China].
OBJECTIVE To investigate the possible association between polymorphism of CC16 gene exon 1 and asthma, the genotype and allele frequencies of CC16 gene exon 1 in the asthmatic patients of HanExpand
  • 5
  • 1
[Cloning and sequence analysis of a new, full-length cDNA fragment of drug resistance-related gene in human lung adenocarcinoma].
BACKGROUND & OBJECTIVE Multi-drug resistance(MDR) is an important cause of chemotherapeutic failure in lung cancer cells. Further studies on drug resistance-related genes in lung cancer by molecularExpand
  • 9
  • 1
Efficacy of Chemotherapeutic Agents Under Hypoxic Conditions in Pulmonary Adenocarcinoma Multidrug Resistant Cell Line
Abstract Hypoxia is often observed in solid tumors. The aim of this study was to investigate the efficacy of seven cytotoxic drugs against the pulmonary adenocarcinoma multidrug-resistant cell lineExpand
  • 8
[Screening and identification for cDNA of differentially expressed genes in human primary hepatocellular carcinoma].
  • J. Li, B. Han, +4 authors J. Chen
  • Biology, Medicine
  • Zhonghua yi xue yi chuan xue za zhi = Zhonghua…
  • 1 February 2003
OBJECTIVE Screening and identification of differentially expressed genes in human primary hepatocellular carcinoma(HCC). METHODS The differentially expressed genes subtracted cDNA library of HCCExpand
  • 6
[The effect of Na(+)/H(+) exchanger-1 (NHE-1) antisense expression vector on NHE-1 gene expression in human lung adenocarcinoma cells and its biological significance].
OBJECTIVE To explore the inhibitory effect of Na(+)/H(+) exchanger-1 (NHE-1) antisense expression vector on NHE-1 gene in human lung neoplasm cells and to observe its biological effect. METHODSExpand
  • 4
[Effect of co-inhibition of MCT1 gene and NHE1 gene on proliferation and growth of human lung adenocarcinoma cells].
BACKGROUND & OBJECTIVE The authors previously discovered that the intracellular pH values (pHi) of tumor cells could be decreased, which led tumor cells to acidify and die, when the expressions ofExpand
  • 1