Guenter Wolf

Hsiu-Ju Chiu2
Ashley M. Deacon2
Marc-André Elsliger2
2Hsiu-Ju Chiu
2Ashley M. Deacon
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Complete automation of the macromolecular crystallography experiment has been achieved at SSRL through the combination of robust mechanized experimental hardware and a flexible control system with an intuitive user interface. These highly reliable systems have enabled crystallography experiments to be carried out from the researchers' home institutions and(More)
A novel aminoacyl-tRNA synthetase that contains an iron-sulfur cluster in the tRNA anticodon-binding region and efficiently charges tRNA with tryptophan has been found in Thermotoga maritima. The crystal structure of TmTrpRS (tryptophanyl-tRNA synthetase; TrpRS; EC reveals an iron-sulfur [4Fe-4S] cluster bound to the tRNA anticodon-binding (TAB)(More)
The Joint Center for Structural Genomics (JCSG), one of four large-scale structure-determination centers funded by the US Protein Structure Initiative (PSI) through the National Institute for General Medical Sciences, has been operating an automated distributed structure-solution pipeline, Xsolve, for well over half a decade. During PSI-2, Xsolve solved,(More)
  • Lakshmanane Premkumar, Christopher L Rife, S Sri Krishna, Daniel McMullan, Mitchell D Miller, Polat Abdubek +47 others
  • 2007
Introduction. Transcriptional regulators play a crucial role in the adaptation of microorganisms to diverse environmental challenges. 1–3 Most microbial transcriptional regulators contain an effector binding regulatory domain and a DNA-binding domain that interacts with a specific operator DNA to either prevent (transcriptional repress-ors) or stimulate(More)
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