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Cell-type plasticity within a tumor has recently been suggested to cause a bidirectional conversion between tumor-initiating stem cells and nonstem cells triggered by an inflammatory stroma. NF-κB represents a key transcription factor within the inflammatory tumor microenvironment. However, NF-κB's function in tumor-initiating cells has not been examined(More)
Wnt pathway deregulation is a common characteristic of many cancers. Only colorectal cancer predominantly harbours mutations in APC, whereas other cancer types (hepatocellular carcinoma, solid pseudopapillary tumours of the pancreas) have activating mutations in β-catenin (CTNNB1). We have compared the dynamics and the potency of β-catenin mutations in(More)
Three methods to construct positive de®nite functions with compact support for the approximation of general geophysical harmonic covariance functions are presented. The theoretical background is given and simulations carried out, for three types of covariance functions associated with the determination of the anomalous gravity potential from gravity(More)
  • S. Perruchot, F. Bouchy, +13 authors D. Tezier
  • 2011
High-precision spectrographs play a key role in exoplanet searches using the radial velocity technique. But at the accuracy level of 1 m.s-1 , required for super-Earth characterization, stability of fiber-fed spectrograph performance is crucial considering variable observing conditions such as seeing, guiding and centering errors and, telescope vignetting.(More)
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